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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIMKLA All Species: 20
Human Site: S319 Identified Species: 55
UniProt: Q8IXN7 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0.13
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8IXN7 NP_775913.2 391 42864 S319 A V L P G L S S P R E K N E P
Chimpanzee Pan troglodytes XP_001164308 695 75464 S623 A V L P G L S S P R E K N E P
Rhesus Macaque Macaca mulatta XP_001088222 645 69087 S573 A V L P G L S S P R E K N E P
Dog Lupus familis XP_539562 391 42844 S319 A V L P G L S S P R E K K E P
Cat Felis silvestris
Mouse Mus musculus Q6PFX8 380 41485 T308 S L L P N R Q T G K M A I L P
Rat Rattus norvegicus XP_001073980 380 41538 T308 S L L P N R Q T G K M A I L P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511443 236 25219 E162 S V V S T A S E T S E P E L G
Chicken Gallus gallus XP_416481 386 42573 L312 S L L T P G R L T R R M S L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q66HZ2 405 44482 S319 S L L S V V S S T S E T S S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 56.2 60.3 96.9 N.A. 87.7 87.9 N.A. 36.3 66.7 N.A. 65.4 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 56.2 60.3 98.2 N.A. 92 92.5 N.A. 44.7 83.1 N.A. 81.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 20 20 N.A. 20 13.3 N.A. 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 93.3 N.A. 46.6 46.6 N.A. 33.3 33.3 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 45 0 0 0 0 12 0 0 0 0 0 23 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 12 0 0 67 0 12 45 12 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 45 12 0 0 23 0 0 0 0 0 12 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 23 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 23 0 45 12 0 0 % K
% Leu: 0 45 89 0 0 45 0 12 0 0 0 0 0 45 12 % L
% Met: 0 0 0 0 0 0 0 0 0 0 23 12 0 0 0 % M
% Asn: 0 0 0 0 23 0 0 0 0 0 0 0 34 0 0 % N
% Pro: 0 0 0 67 12 0 0 0 45 0 0 12 0 0 67 % P
% Gln: 0 0 0 0 0 0 23 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 23 12 0 0 56 12 0 0 0 0 % R
% Ser: 56 0 0 23 0 0 67 56 0 23 0 0 23 12 0 % S
% Thr: 0 0 0 12 12 0 0 23 34 0 0 12 0 0 0 % T
% Val: 0 56 12 0 12 12 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _